Maxxam’s Forensic Equine Drug Testing laboratory undertakes research projects involving:
- method development for new drugs,
- method transfer from other laboratories,
- drug metabolism studies, and
- analysis of equine blood and urine to produce data for elimination studies.
Our research scientists work closely with Official Chemists in the racing industry to ensure that forensically appropriate methods are employed for routine analysis.
All qualitative and quantitative methods are scientifically validated before being used in analytical drug elimination studies. Our research scientists are also called upon to conduct non-routine analyses associated with drug related investigations conducted by provincial regulatory bodies in Canada.
Maxxam’s FEDT group is internationally renowned for their contributions to the science of doping control through publication in peer-reviewed literature and presentations at scientific meetings.
- Quantitation of γ-aminobutyric acid in equine plasma by hydrophilic interaction liquid chromatography with tandem mass spectrometry. Journal of Separation Science. 2017, 40, 3239-3247. Rong Yi, Sarah Zhao, Noel Kong, Julia Zhang, Devan Loganathan Sandrine Mérette & Barbara Morrissey.
- A highly sensitive method for the detection of desmopressin in horse plasma & urine. Proceedings of the 21st International Conference of Racing Analysts & Veterinarians, Uruguay. 2016, 184-191. Rong Yi, Noel Kong, Julia Zhang, Devan Loganathan, Sandrine Mérette & Barbara Morrissey.
- “Na-(2,4-dinitro-5-fluorophenyl)-L-valinamide”, a cost effective chiral derivatizing reagent for the rapid resolution of enantiomers by HPLC-MS/MS in equine plasma and urine. Proceedings of the 21st International Conference of Racing Analysts & Veterinarians, Uruguay. 2016, 338-347. Devan Loganathan, Julia Zhang, Noel Kong, Rong Yi, Sandrine Mérette & Barbara Morrissey.
- Detection of efaproxiral (RSR13) and its metabolites in equine by liquid chromatography tandem mass spectrometry. Journal of Mass Spectrometry. 2014, 49, 57-67. Rong Yi, Jasmeet Sandhu, Sarah Zhao, Geoffrey Lam, Devan Loganathan & Barbara Morrissey.
- Detection of myo-inositol tris pyrophosphate (ITPP) in equine following an administration of ITPP. Drug Testing and Analysis. 2014, 6, 268-276. Geoffrey Lam, Sarah Zhao, Jasmeet Sandhu, Rong Yi, Devan Loganathan & Barbara Morrissey.